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Loneliness increases dementia risk by 31%: study

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By Amber Roman

22 Oct 2024, 17:54 PM EDT

A recent study has revealed that loneliness significantly increases the risk of developing dementia, regardless of age or gender. Researchers at Florida State University analyzed data from more than 600,000 people worldwide, showing that feelings of loneliness raise the risk of dementia by 31%. This research, published in the journal Nature Mental Healthprovides critical insight into how loneliness impacts the cognitive health of older adults, with important implications for future public health interventions.

Loneliness, defined as dissatisfaction with social relationships, can have devastating effects on cognitive functioning. Associate Professor Martina Luchetti, who led the study, said this finding is not surprising given growing evidence linking loneliness to poor physical and mental health. Dementia, he explained, is a condition that develops slowly, with neuropathological changes that can begin decades before clinical symptoms manifest. Understanding the relationship between loneliness and cognitive decline in all its stages is essential to develop better prevention and treatment strategies.

The study is the largest meta-analysis to date on the relationship between loneliness and dementia, and included 21 longitudinal studies spanning diverse cultures and regions of the world. Although most of the data comes from countries in the Western Hemisphere, the team stressed the need to expand the research to include more data from low-income countries. This is crucial because an increase in dementia cases has been observed in these regions, suggesting that loneliness may have different effects depending on the cultural and economic context.

Research also links loneliness to specific causes of dementia, such as Alzheimer’s disease, and to cognitive decline that can occur before a formal diagnosis is made. This reinforces the idea that addressing loneliness could be key to reducing the risk of dementia in the aging population. Given that the effects of loneliness do not discriminate by age or sex, researchers suggest that interventions aimed at reducing it should be a priority in public health policies, especially in the context of a rapidly aging global population.

Luchetti noted that the COVID-19 pandemic exacerbated levels of loneliness due to social restrictions imposed to control the virus, drawing attention to loneliness as a public health crisis. Both the World Health Organization and the United States Surgeon General have declared loneliness an urgent public health problem. This context prompted the research team to delve deeper into the effects of loneliness on dementia risk, especially in older adults, a group that is already vulnerable to both loneliness and cognitive diseases.

Given the strong link established between loneliness and dementia, the next step in research is to identify the causes of loneliness and develop effective interventions to combat it. This could include programs that promote social connectedness among older adults or encourage access to community support networks, particularly in those countries where health and social welfare systems are less robust.

The study, funded by the National Institute on Aging of the National Institutes of Health, has been welcomed as an important advance in understanding how psychosocial factors influence cognitive health. In addition to researchers from Florida State University, scientists from Wenzhou Medical University, the University of Limerick and the University of Montpelier participated.

These types of studies highlight the need for a multidisciplinary approach to address dementia, combining biological, psychological and social factors. As the world’s population ages, understanding how loneliness contributes to cognitive decline will be crucial to designing public policies and health programs focused on improving the quality of life of older adults. The evidence is clear: reducing loneliness not only improves emotional well-being, but could also be an essential tool in preventing dementia in millions of people around the world.

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