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The secret of obesity may lie in genes and not in diet or exercise: study

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By Amber Roman

11 Oct 2023, 16:48 PM EDT

In an effort to address the growing problem of obesity around the world, an international team of leading researchers recently published an article in the prestigious journal Science.

This article was based on the results of an academic conference organized by the Royal Society, in which experts and academics in the field of obesity research came together to discuss the possible mechanisms of pathogenesis of this health epidemic.

The lead authors of this paper, Prof. John Speakman of the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences, Prof. Kevin Hall of the US National Institutes of Health, Prof. Thorkild Sorensen of the University of Copenhagen and Prof. David Allison of Indiana University (USA), joined forces in an unprecedented collaborative effort to shed light on one of the most pressing health challenges of our time .

Obesity, a persistent global problem

Obesity is a global public health problem that has baffled governments around the world for decades. Despite efforts to combat it, obesity rates continue to rise, and strategies that have revolved around promoting physical activity and restricting advertising of unhealthy foods have proven insufficient.

One of the main obstacles in the fight against obesity has been the persistence of misconceptions. The idea that obesity is simply the result of consuming more calories than are burned through exercise has proven to be simplistic. Instead, it has become clear that obesity is the result of a complex interaction between genetics, environment, and physiology.

Recent advances in obesity research have been notable. One of the most important findings has been the identification of leptin, a hormone produced by fat cells, which plays a central role in regulating food consumption by activating signals in the brain.

This revelation has transformed the traditional view of adipose tissue as a mere passive energy reserve., and its active role in the production of hormones that affect the body as a whole has been recognized. Despite these advances, the obesity epidemic remains a significant challenge.

Prof. John Speakman, lead author of the paper, commented: “There are clearly fundamental answers we should have. Obesity represents a significant challenge to global health, and recognizing our progress to date is essential to chart a path forward. Addressing these vital unanswered questions could serve as a roadmap to prioritize research efforts and collaborate globally in the fight against this growing obesity epidemic.”

This represents an important step in the quest for a deeper understanding of obesity and raises crucial questions that must be answered to effectively address this global health issue.

Obesity is a multifaceted challenge that requires continued international collaboration between scientists, clinicians and policy makers to develop more effective prevention and treatment strategies. Ongoing research in this field is essential to curb weight gain and improve the health of populations around the world.

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