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Researchers have discovered the vital role of a hormone that is developed in males during puberty and could predict the likelihood that certain diseases develop in the future.
The insulin-like peptide hormone, called INSL3, was discovered by scientists at the University of Nottingham.
This is consistent over long periods of time and is an important early biomarker for the prediction of age-related diseases.
The findings published this Tuesday in Frontiers in Endocrinology ensure that INSL3 is produced by the same cells in the testicles that produce testosterone, but unlike of testosterone, which fluctuates throughout a man’s life, INSL3 remains constant.
It means that s e remains with the level at puberty practically the same throughout a man’s life, decreasing only slightly in old age.
This becomes the first clear and reliable predictive biomarker of age-related morbidity compared to any other measurable parameter.
Age-related diseases
The results showed that the level of INSL3 in the blood correlates with a number of age-related diseases, such as bone weakness, sexual dysfunction, diabetes, and cardiovascular disease. .
The discovery of the constant nature of this hormone is very important, as it means that a man with a high INSL3 when he is young will continue to have a high INSL3 when he is older.
But someone who already has a low INSL3 at a young age will have a low INSL3 when he is older, l or that it will make you more prone to acquiring typical age-related diseases.
Opportunities are not only opening up to predict age-related diseases, but to find ways to prevent the onset of these diseases with early intervention.
The research was led by Professor Ravinder Anand-Ivell and Professor Richard Ivell, and is the latest of three recent studies on this hormone.
Anand-Ivell explains that this aging research narrows the fitness gap that appears as people age.
“Our Hormone discovery is an important step in understanding this and will pave the way not only to help individuals individually, but also to help alleviate the care crisis we face as a society,” he stated.
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